I originally had a post on how to clean up WinSXS from 2014. However, I have come across a program that I have tested, and works very well.
The program is Patch Cleaner. This program scans your Installer folder to check if there are orphan files relating to programs or patches you may have removed from your computer. Any orphan files Patch Cleaner locates can be removed.
I have tested Patch Cleaner on Server 2012 and 2012 R2, including production terminal servers with 100 users. I have no had any issues thus far.
With Server 2012, running Patch Cleaner was removing on average 20GB+ on each server.
I would recommend checking this out if you are still stuck for space.
You may have come across this issue when you’ve upgraded your computer to Windows 10. Upon returning to your computer, the screen refreshes slowly and applications appear to have crashed due to memory issue.
There have been many suggest ways to fix this, but the simplest way is to do the following:
Open Regedit by pressing Windows Key + R and typing regedit
Navigate to HKEY_LOCAL_MACHINESYSTEMCurrentControlSetControlSession ManagerMemory Management
Change the value of ClearPageFileAtShutDown to 1
Reboot your computer
This will wipe the page file on reboot.
This may increase the shutdown time of your computer, but it will fix this error. The root cause of this error is an incompatible driver on your system. I will follow up with an article on this process.